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Silent Cerebral Infarctions in Patients with Late-Onset Mania
Stroke 26:946-949, Fujikawa,T.,et al, 1995
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Article Abstract
The incidence of SCIs in patients with late-onset mania was 65.0%this incidence was significantly higher than that of patients with early-onset affective disorders(P<.05).The incidence of the mixed type of SCI was 50. 0%in patients with late-onset mania;this was significantly higher than that in patients with late-onset major depression(P<.05).Our findings suggest that approximately half of the cases of late-onset mania might be secondary mania related to SCIs.Because the mixed type of SCI is more prevalent in the patients with late-onset mania than in those with late- onset major depression,mania may be associated with the larger areas of brain damage and hence may be a more serious form of affective illness than major depression.
 
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affective disorders
asymptomatic
cerebral infarction
cerebrovascular accident
cerebrovascular accident,silent
mania
manic-depressive
MRI
MRI,abnormal
old age,neurology of
psychiatric disorder
psychiatric problems in neurologic disorders

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